RADIESSE^® for Lower Face

A Definition All Your Own

RADIESSE provides natural definition by restoring a more youthful-looking appearance.^1-2

You’ve worked your whole life at defining who you are. Facial wrinkles and folds shouldn’t affect that. Learn how the qualities of RADIESSE work to stimulate your body’s own natural production of collagen^1,2 for a more refreshed appearance–an appearance you’ve spent years defining.

A Definition All Your Own

RADIESSE provides natural definition by restoring a more youthful-looking appearance.^1-2

You’ve worked your whole life at defining who you are. Facial wrinkles and folds shouldn’t affect that. Learn how the qualities of RADIESSE work to stimulate your body’s own natural production of collagen^1,2 for a more refreshed appearance–an appearance you’ve spent years defining.

In my work, appearance is vital... it’s all about a stunning presentation.

Leanne, 46 • Landscape Architect & Actual RADIESSE^® Patient

Smile Lines

Deep smile lines (nasolabial folds) can give your face a tired and aged expression.
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Marionette Lines

These lines can make you look like you’re scowling, even when you’re not.
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Pre-jowl Folds

This area can look hollow as volume loss causes the skin to sag along your jawline and create folds.
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Corners of the Mouth

A downturned appearance of the mouth can make you look tired, angry, or sad.
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Chin Wrinkles

The lines across your chin can distract from your smile and make you look older.
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Take a closer look at the faces of RADIESSE to see how instant lift and long-lasting definition work together to smooth wrinkles and folds.^3,4

LeAnne, 46

Results after 2 weeks*

Provides immediate lift and restores lost volume in areas of the lower face.^4,5
Helps restore a more natural-looking and youthful appearance.⁴

Face Before-and-After Pictures

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What are RADIESSE^®, RADIESSE^® (+), and BELOTERO BALANCE?

RADIESSE^®, RADIESSE^® (+), and BELOTERO BALANCE are dermal fillers that are FDA-approved to smooth moderate to severe facial wrinkles and folds, such as nasolabial folds (the creases that extend from the corner of your nose to the corner of your mouth). RADIESSE^® is also used for correcting volume loss in the back of the hands.

BELOTERO BALANCE, RADIESSE^®, and RADIESSE^® (+) IMPORTANT SAFETY INFORMATION

Who should not use RADIESSE^®, RADIESSE^® (+), or BELOTERO BALANCE?

You should not use RADIESSE^®, RADIESSE^® (+), or BELOTERO BALANCE if you have a history of severe allergies or anaphylaxis, or if you are pregnant or breastfeeding.

You should not use RADIESSE^® or RADIESSE^® (+) if you have an allergy to any part of the product, or if you have a bleeding disorder.

You should not use RADIESSE^® (+) if you have an allergy to lidocaine or medicines like it.

You should not use BELOTERO BALANCE if you have an allergy to gram-positive bacterial proteins.

What is the most important information I should know about RADIESSE^®, RADIESSE^® (+), and BELOTERO BALANCE?

One of the risks with using these products is unintentional injection into a blood vessel. The chances of this happening are very small, but if it does happen, the complications can be serious, and may be permanent. These complications, which have been reported for facial injections, can include vision abnormalities, blindness, stroke, temporary scabs, or permanent scarring of the skin. If you have changes in your vision, signs of a stroke (including sudden difficulty speaking, numbness or weakness in your face, arms, or legs, difficulty walking, face drooping, severe headache, dizziness, or confusion), white appearance of the skin, or unusual pain during or shortly after treatment, you should notify your health care practitioner immediately.

As with all procedures that involve an injection through the skin, there is a risk of infection.

The safety and effectiveness of RADIESSE^®, RADIESSE^® (+) or BELOTERO BALANCE in parts of the face other than facial wrinkles and folds has not been established.

Do not use RADIESSE^®, RADIESSE^® (+), or BELOTERO BALANCE if you have a skin infection or inflammation until it has healed.

The microspheres in RADIESSE^® and RADIESSE^® (+) can be seen in X-rays and CT Scans. It is very important that you tell your health care provider that you have had RADIESSE^® or RADIESSE^® (+) dermal filler.

If you have a history of herpes, you may experience a herpes breakout after treatment.

Injection in the back of the hand may result in temporary difficulty performing activities. RADIESSE^® may cause nodules, bumps or lumps in the back of the hand and can last up to 1 year.

You should minimize strenuous activity and avoid extensive sun or heat exposure for about 24 hours after treatment and until any swelling or redness has resolved.

What should I tell my doctor before using RADIESSE^®, RADIESSE^® (+), or BELOTERO BALANCE?

Tell your health care provider if you are taking blood thinners or medicines that can interfere with the clotting of blood, such as aspirin or warfarin. These medicines might make it more likely that you will experience bruising or bleeding at the injection site. Tell your health care provider if you have any diseases, injuries or disabilities of the hand, if you have a history of forming large, raised scars, or if you have had any other skin treatments such as skin peels.

Before treatment with BELOTERO BALANCE, tell your doctor if you have frequent sore throats, or if you are on any immunosuppressive therapy.

What are the most common adverse events with RADIESSE^®, RADIESSE^® (+), or BELOTERO BALANCE?

The most common adverse events seen in clinical studies of RADIESSE^® used in the hands include bruising, redness, swelling, pain, itching, nodules or bumps/lumps, difficulty performing activities, loss of sensation and other local side effects. The most common adverse events seen in clinical studies of RADIESSE^® or RADIESSE^® (+) used in the face include bruising, redness, swelling, pain, itching and other local side effects.

The most common adverse events seen in clinical studies with BELOTERO BALANCE were swelling, bruising, redness, hardening of the skin, pain, altered color or itching. Other adverse events that have occurred with BELOTERO BALANCE include headache, swelling of the side of the nose, moderate cold sore, lip numbness, and lip dryness. Side effects were often mild to moderate and usually resolved within 7 days.

These are not all of the possible side effects with RADIESSE^®, RADIESSE^® (+), or BELOTERO BALANCE. Merz collects information about adverse events seen with these products post-approval. These events are included in the RADIESSE^®, RADIESSE^® (+), and BELOTERO BALANCE Patient Information Guide based on an assessment of seriousness and potential causal relationship to the products. Please see the Patient Information Guides available at www.radiesse.com and www.belotero.com for a list of these events. Tell your health care provider about any side effects that bother you or do not go away.

Important: For full safety information, please visit www.radiesse.com, www.belotero.com, or call MyMerz Solutions at 1-844-469-6379

RADIESSE^®, RADIESSE^® (+), and BELOTERO BALANCE are available by prescription only.

RADIESSE^® is available only through licensed physicians.

Enter your zip code to find a licensed RADIESSE^® provider.